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3 May 2024
16:00-18:00
Session 1 – Old paradigms, new concepts
Chairpersons: Hasan Yazıcı (Türkiye), Isabelle Touitou (France)
16:00-16:20
Unmet needs in FMF
Huri Özdoğan (Türkiye)
16:20-16:50
Old paradigms and new concepts in FMF
Eldad Ben-Chetrit (Israel)
16:50-17:20
What is FMF?
Ahmet Gül (Türkiye)
17:20-17:50
Review of the last two year
Yelda Bilginer (Türkiye)
19:00
Welcome Reception
4 May 2024
08:00-10:00
Session 2 – Update: Genetics and Pathogenesis
Chairpersons: Ahmet Gül (Türkiye),Tillmann Kallinich (Germany),Banu Peynircioğlu (Türkiye)
08:00-08:30
The changing concept of one gene-one phenotype in monogenic autoinflammatory diseases
Ivona Aksentijevich (USA)
08:30-09:00
Regulation of pyrin inflammasome
Mohamed Lamkanfi (Belgium)
09:00-09:20
Pyroptosis and clinical implications in FMF
Helmut Wittkowski (Germany)
09:20-09:40
Pyrin inflammasome and inflammatory cell migration in FMF
Tayfun Hilmi Akbaba (Türkiye)
09:40-10:00
Discussion
10:00-10:30
Coffee Break
10:30-12:00
Session 3 – Update: Genetic diagnosis, environmental factors and microbiome
Chairpersons: Seza Özen(Türkiye), Dorota Rowczenio (UK)
10:30-11:00
Update: genetic diagnosis in FMF
Isabelle Touitou (France)
11:00-11:20
Non-MEFV gen variants in patients with a FMF phenotype
Eda Tahir Turanlı (Türkiye)
11:20-11:40
Syndrome of Undifferentiated Recurrent Fever (SURF)
Marco Gattorno (Italy)
11:40-12:00
Impact of enviromental factors and microbiome on the pathogenesis of FMF
Sophie Georgin Lavialle (France)
12:00-12:30
Oral presentations
Chairpersons: Fatoş Önen (Türkiye), Ömer Karadağ (Türkiye)
12:00-12:07
A clinical overview of unclassified systemic autoinflammatory diseases followed in a Turkish Pediatric Referral Center (Ref: 115)
Şengül Çağlayan (Türkiye)
12:07-12:14
Evaluation of patients carrying variants of unknown significance (VUS) in a large FMF cohort: A single center study (Ref: 116)
Taner Coşkuner (Türkiye)
12:14-12:21
Exploring S100A8/A9, Neopterin, and MMP3 in Familial Mediterranean Fever: Insights into pathogenesis and diagnostic significance (Ref: 145)
Özgür Can Kılınc (Türkiye)
12:21-12:28
Epidemiological features and clinical manifestations in lebanese and Italian subjects with Familial Mediterranean Fever (Ref: 130)
Nour Jaber (Italy)
12:30-13:30
Lunch & Poster Reviewing
13:30-15:30
Session 4 – Criteria, registry, geography
Chairpersons: Helmut Wittkowski (Germany), Fatoş Yalçınkaya (Türkiye)
13:30-13:50
Pros and cons of diagnostic and classification criteria for FMF
Isabelle Kone-Paut (France)
13:50-14:10
Challenges of preparing a registry for FMF
Marco Gattorno (Italy)
14:10-14:20
Discussion
14:20-15:30
Round Table: FMF around the world 
Chairpersons: Seza Özen (Türkiye), Huri Özdoğan (Türkiye),Eldad Ben-Chetrit (Israel)
14:20-14:35
FMF in Japan
Tomohiro Koga (Japan)
14:35-14:50
FMF in Italy
Raffaele Manna (Italy)
14:50-15:05
FMF in Saudi Arabia
Sulaiman Al-Mayouf (Saudi Arabia)
15:05-15:30
Discussion
15:30-16:00
Coffee Break 
16:00-17:40
Session 5 – Update: Amyloidosis, associated diseases
Helen Lachmann (UK), Cengiz Korkmaz (Türkiye),Melike Melikoğlu (Türkiye)
16:00-16:20
Is amyloidosis still a threat in FMF?
Ahmet Gül (Türkiye)
16:20-16:40
Early versus late onset FMF
Piero Portincasa (Italy)
16:40-17:00
PFAPA and FMF
Özgür Kasapçopur (Türkiye)
17:00-17:20
AS and enthesitis in FMF
Servet Akar (Türkiye)
17:20-17:40
Behçet’s disease and FMF
Emire Seyahi (Türkiye)
17:40-18:08
Oral presentations
Chairpersons: Mikail Kostik (Russia), Hakan Babaoğlu (Türkiye)
17:40-17:47
Gender differences in the diagnosis delay of familial Mediterranean fever: A JIR cohort study (Ref: 91)
Rim Bourguiba (Tunisia)
17:47-17:54
Cardiovascular comorbidities in patients with Familial Mediterranean Fever over 45 years of age (Ref: 133)
Sejla Karup (Türkiye)
17:54-18:01
Male fertility and paternal effect on pregnancy outcomes in FMF (Ref: 150)
Kerem Parlar (Türkiye)
18:01-18:08
Menstrual cycle patterns and dysmenorrhea frequency in adolescent girls with familial Mediterranean fever: Cross-Sectional case-control study (Ref: 106)
Fatma Gül Demirkan (Türkiye)
5 May 2024
08:00-10:00
Session 6a. – Upate:Treatment-I
Chairpersons: Huri Özdoğan(Türkiye),Sophie Georgin-Lavialle (France),Serdal Uğurlu (Türkiye)
08:00-08:20
Mechanism of action of colchicine and its expanding efficacy
Eldad Ben-Chetrit (Israel)
08:20-08:40
Colchicine response and tolerance in FMF
Seza Özen (Türkiye)
08:40-09:00
Anti-IL1 treatment in FMF
Serdal Uğurlu (Türkiye)
09:00-09:15
On-demand anti-IL1 treatment
Ilan Ben-Zvi (Israel)
09:15-09:40
Efficacy and safety of anti-IL1β treatment in FMF
Helen Lachmann (UK)
09:40-10:00
Anti-IL6 treatment FMF
Tomohiro Koga (Japan)
10:00-10:30
Coffee Break 
10:30-12:30
Session 6b. – Update: Treatment II
Chairpersons: Ahmet Gül(Türkiye),Isabelle Kone-Paut (France)
10:30-10:50
Biologic agent combinations in the management of FMF and other autoinflammatory diseases
Abdurrahman Tufan (Türkiye)
10:50-11:10
Treat-to target strategies in FMF
Tillmann Kallinich (Germany)
11:10-11:40
Discussion for sessions 6a and 6b
11:40-12:30
Session 7 – Transition 
Chairpersons:  Kenan Barut (Türkiye), Gülay Özgön (Türkiye),Amra Adrovich (Türkiye)
11:40-12:00
Transition from pediatric to adult FMF clinics
Betül Sözeri (Türkiye)
12:00-12:42
Oral presentations
12:00-12:07
Machine learning algorithms to predict colchicine resistance in Familial Mediterranean Fever (Ref: 158)
Admir Öztürk (Türkiye)
12:07-12:14
Comparing the effects of treatments during the attack period on clinical and laboratory data in Familial Mediterranean Fever Patients (Ref: 143)
Elif Kılıç Konte (Türkiye)
12:14-12:21
Familial Mediterranean Fever: Effective follow-up of patients who ceased colchicine treatment (Ref: 122)
Gülcan Özomay Baykal (Türkiye)
12:21-12:28
Canakinumab treatment in patients with colchicine-resistant familial Mediterranean fever: a multicenter observational study (Ref: 83)
Mete Kara (Türkiye)
12:28-12:35
Is canakinumab a good tool for the undifferentiated autoinflammatory diseases: the data of retrospective cohort study (Ref: 108)
Mikhail Kostik (Russia)
12:35-12:42
Familial Mediterranean Fever from childhood to adulthood (Ref: 163)
Zeynep Balık (Türkiye)
12:42-12:50
Discussion
12:50-13:10
Highlights of the meeting
Sezgin Şahin (Türkiye)
13:10-13:30
Future perspectives, presentation of awards, closing remarks
Huri Özdoğan (Türkiye), Eldad Ben-Chetrit (Israel),Serdal Uğurlu (Türkiye)